The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2024
Filed:
Oct. 20, 2022
Massachusetts Institute of Technology, Cambridge, MA (US);
Jeremiah A. Johnson, Boston, MA (US);
Hung Vanthanh Nguyen, Braintree, MA (US);
Peyton Shieh, Cambridge, MA (US);
Wencong Wang, Cambridge, MA (US);
Bin Liu, Hopkinton, MA (US);
Valerie Lensch, Cambridge, MA (US);
Landon Kilgallon, Cambridge, MA (US);
Yutong Dai, Somerville, MA (US);
Samantha Lynn Kristufek, Lubbock, TX (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Abstract
The present disclosure provides enynes, end-functionalized polymers, conjugates, methods of preparation, compositions, kits, and methods of use. The conjugates comprise at least (1) a peptide (e.g., an antibody), protein, nucleoprotein, mucoprotein, lipoprotein, glycoprotein, or polynucleotide; and (2) a polymer comprising a pharmaceutical agent. The conjugates may be useful in delivering (e.g., targeted delivering) the pharmaceutical agent to a subject in need thereof or cell or treating, preventing, or diagnosing a disease.