The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 10, 2024

Filed:

Jul. 10, 2020
Applicant:

Waters Technologies Corporation, Milford, MA (US);

Inventors:

Darryl W. Brousmiche, Grafton, MA (US);

Jacob N. Fairchild, Upton, MA (US);

Jason F. Hill, Milford, MA (US);

Giorgis Isaac, Marlborough, MA (US);

Michael F. Morris, Ashland, MA (US);

Kevin D. Wyndham, Upton, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01D 15/26 (2006.01); B01D 15/30 (2006.01); B01D 15/32 (2006.01); B01D 15/40 (2006.01); B01D 53/02 (2006.01); B01J 20/22 (2006.01); B01J 20/28 (2006.01); B01J 20/282 (2006.01); B01J 20/283 (2006.01); B01J 20/284 (2006.01); B01J 20/285 (2006.01); B01J 20/288 (2006.01); B01J 20/289 (2006.01); B01J 20/30 (2006.01); B01J 20/32 (2006.01); C07F 7/18 (2006.01);
U.S. Cl.
CPC ...
B01J 20/283 (2013.01); B01D 15/26 (2013.01); B01D 15/30 (2013.01); B01D 15/305 (2013.01); B01D 15/322 (2013.01); B01D 15/40 (2013.01); B01D 53/025 (2013.01); B01J 20/22 (2013.01); B01J 20/28004 (2013.01); B01J 20/28016 (2013.01); B01J 20/28042 (2013.01); B01J 20/28057 (2013.01); B01J 20/28059 (2013.01); B01J 20/28061 (2013.01); B01J 20/28064 (2013.01); B01J 20/28066 (2013.01); B01J 20/28069 (2013.01); B01J 20/28071 (2013.01); B01J 20/28073 (2013.01); B01J 20/28076 (2013.01); B01J 20/28078 (2013.01); B01J 20/28083 (2013.01); B01J 20/28085 (2013.01); B01J 20/288 (2013.01); B01J 20/289 (2013.01); B01J 20/3085 (2013.01); B01J 20/3204 (2013.01); B01J 20/3206 (2013.01); B01J 20/3208 (2013.01); B01J 20/3246 (2013.01); B01J 20/3285 (2013.01); B01J 20/3293 (2013.01); C07F 7/1804 (2013.01); B01J 20/282 (2013.01); B01J 20/284 (2013.01); B01J 20/285 (2013.01); B01J 20/32 (2013.01); B01J 20/3234 (2013.01); B01J 2220/54 (2013.01); B01J 2220/80 (2013.01);
Abstract

The present disclosure relates to a method of separating a compound of interest, particularly unsaturated compound(s) of interest, from a mixture. The compound is separated using a column having a chromatographic stationary phase material for various different modes of chromatography containing a first substituent and a second substituent. The first substituent minimizes compound retention variation over time under chromatographic conditions. The second substituent chromatographically and selectively retains the compound by incorporating one or more aromatic, polyaromatic, heterocyclic aromatic, or polyheterocyclic aromatic hydrocarbon groups, each group being optionally substituted with an aliphatic group. In some examples, the present disclosure can include a chromatographic system having a chromatographic column having a stationary phase with a chromatographic substrate containing silica, metal oxide, an inorganic-organic hybrid material, a group of block copolymers, or a combination thereof.


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