The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2024
Filed:
Sep. 12, 2022
Applicants:
Northwestern University, Evanston, IL (US);
Chapman University, Orange, CA (US);
Inventors:
Richard B. Silverman, Winnetka, IL (US);
Sun Yang, Lake Forest, CA (US);
Assignees:
Northwestern University, Evanston, IL (US);
Chapman University, Orange, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/47 (2006.01); A61K 31/381 (2006.01); A61K 31/4164 (2006.01); A61K 31/495 (2006.01); A61K 38/21 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 31/47 (2013.01); A61K 31/381 (2013.01); A61P 35/00 (2018.01); A61K 31/4164 (2013.01); A61K 31/495 (2013.01); A61K 38/212 (2013.01); C07K 16/2818 (2013.01);
Abstract
Disclosed herein are methods and compositions for administering immunotherapy to a subject in need thereof and for treating a subject in need thereof, where in the methods the subject is administered an effective amount of an inhibitor of nNOS for inducing an immunotherapeutic response in the subject and for treating the subject. The disclosed methods and composition may be utilized for treating a subject having a cell proliferative disease or disorder such as melanoma.