The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 10, 2024

Filed:

May. 11, 2022
Applicant:

Case Western Reserve University, Cleveland, OH (US);

Inventors:

Benjamin M. Gaston, Indianapolis, IN (US);

Stephen J. Lewis, Cleveland, OH (US);

Assignee:

CASE WESTERN RESERVE UNIVERSITY, Cleveland, OH (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/225 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01); A61K 31/24 (2006.01); A61K 31/485 (2006.01);
U.S. Cl.
CPC ...
A61K 31/225 (2013.01); A61K 9/0019 (2013.01); A61K 45/06 (2013.01);
Abstract

A method of attenuating opioid induced ventilatory and/or respiratory depression and/or augmenting opioid induced analgesia in a subject in need thereof includes administering to the subject a therapeutically effective amount of a composition comprising a cystine ester or an adduct, a pharmaceutically acceptable salt, a tautomer, or a solvate thereof.


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