The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2024
Filed:
Jun. 27, 2016
The Research Foundation for the State University of New York, Albany, NY (US);
Children's Medical Center Corporation, Boston, MA (US);
Arun Richard Chandrasekaran, Albany, NY (US);
Clinton H. Hansen, Cambridge, MA (US);
Mounir Ahmad Koussa, Somerville, MA (US);
Kenneth Anders Halvorsen, Glenmont, NY (US);
Wesley Philip Wong, Cambridge, MA (US);
The Research Foundation for The State University of New York, Albany, NY (US);
Children's Medical Center Corporation, Boston, MA (US);
Abstract
Provided herein are nucleic acid-based nanoswitches that can detect specific nucleic acids and other analytes types by for example a simple gel electrophoresis readout. Binding of the target to the nanoswitches induces a conformation change from a linear, open conformation to a looped, closed conformation. These nanoswitches may be used in diagnostic assays such as nucleic acid-based diagnostic assays, to detect, measure and/or purify a variety of targets including low abundance targets.