The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2024
Filed:
May. 29, 2018
Applicant:
Ucb Biopharma Srl, Brussels, BE;
Inventors:
Bassem Ben Yahia, Brussels, BE;
Laetitia Malphettes, Brussels, BE;
Nadine Kochanowski, Brussels, BE;
Gill Renner, Slough, GB;
Sandrine Durran, Slough, GB;
Andrew Jeffrey Yates, Slough, GB;
Assignee:
UCB BIOPHARMA SRL, Brussels, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/02 (2006.01); C07K 1/16 (2006.01); C07K 16/00 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
C12P 21/02 (2013.01); C07K 1/16 (2013.01); C07K 16/00 (2013.01); C12N 5/0018 (2013.01); C07K 2317/14 (2013.01); C07K 2317/565 (2013.01); C12N 2500/32 (2013.01); C12N 2510/02 (2013.01); C12N 2511/00 (2013.01); C12N 2523/00 (2013.01);
Abstract
The present invention relates to the use of limited amounts of cysteine and tryptophan in the cell culture medium during production of recombinant proteins, and in particular antibodies. Proteins and antibodies produced under such controlled conditions exhibit reduced heterogeneity, in particular reduced charge variants heterogeneity.
Ben Yahia, Bassem. (2024). Cell culture methods (U.S. Patent No. 12077796). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12077796
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile