The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2024
Filed:
Aug. 23, 2021
Applicants:
University of Maryland, Baltimore, Baltimore, MD (US);
University of Washington, Seattle, WA (US);
Inventors:
Robert K. Ernst, Silver Spring, MD (US);
Mark Pelletier, Brunswick, MD (US);
Adeline Hajjar, Seattle, WA (US);
Assignees:
University of Maryland, Baltimore, Baltimore, MD (US);
University of Washington, Seattle, WA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 11/04 (2006.01); A61K 31/739 (2006.01); A61K 39/02 (2006.01); A61K 39/39 (2006.01); C12P 19/12 (2006.01); C12P 19/26 (2006.01); C12P 19/44 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12P 19/12 (2013.01); A61K 31/739 (2013.01); A61K 39/0291 (2013.01); A61K 39/099 (2013.01); A61K 39/39 (2013.01); C07H 11/04 (2013.01); C12P 19/26 (2013.01); C12P 19/44 (2013.01); A61K 2039/55572 (2013.01);
Abstract
Embodiments of the disclosure provide for unique lipooligosaccharide/lipid A-based mimetics for use as adjuvants. Methods of generating lipooligosaccharide/lipid A-based mimetics are provided that utilize recombinantly engineered bacteria to produce the mimetics, including, for example, addition of one or more particular enzymes such as acyltransferases, deacylases, phosphatases, or glycosyltransferases.