The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2024
Filed:
Dec. 23, 2021
Applicant:
Resolve Therapeutics, Llc, St. Petersburg, FL (US);
Inventors:
James Arthur Posada, St. Petersburg, FL (US);
Sanjay Patel, San Diego, CA (US);
Weihong Yu, San Diego, CA (US);
Chris Gabel, Seattle, WA (US);
Assignee:
Resolve Therapeutics, LLC, Miami, FL (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/22 (2013.01); C12Y 301/21001 (2013.01); C12Y 301/27005 (2013.01); A61K 38/00 (2013.01); C07K 2317/72 (2013.01); C07K 2319/30 (2013.01);
Abstract
The invention provides for optimized binuclease fusion proteins with increased pharmacokinetic properties. The optimized binuclease fusion proteins of the invention two or more nuclease domains (e.g., RNase and DNase domain) operably coupled to an Fc domain. The invention also provides methods of treating or preventing a condition associated with an abnormal immune response.