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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12077781 B1

PDFFull Text
Date of Patent:
Sep. 03, 2024

Filed:

Dec. 19, 2019

Cardiomyocyte preparation and preparation method therefor and use thereof

Applicant:

Help Stem Cell Innovations Co., Ltd., Suzhou, CN;

Inventors:

Jiaxian Wang, Suzhou, CN;

Qian Wang, Suzhou, CN;

Yat Ping Tsui, Suzhou, CN;

Xiao Xu, Suzhou, CN;

Assignee:

HELP STEM CELL INNOVATIONS CO., LTD., Jiangsu, CN;

Attorney:

CANTOR COLBURN LLP

Primary Examiner:

Allison M Fox

Int. Cl.
CPC ...
C12N 5/077 (2010.01); A61K 9/00 (2006.01); A61K 35/33 (2015.01); A61K 35/34 (2015.01); A61P 9/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0657 (2013.01); A61K 9/0019 (2013.01); A61K 35/33 (2013.01); A61K 35/34 (2013.01); A61P 9/00 (2018.01); C12N 5/0656 (2013.01); C12N 2506/02 (2013.01); C12N 2506/45 (2013.01);
Abstract

Provided are a cardiomyocyte preparation, a preparation method therefor and the use of the preparation in treating heart failure. The cardiomyocyte preparation comprises cardiomyocytes and fibroblasts, differentiated from pluripotent stem cells, wherein the concentration of the cardiomyocytes in the cardiomyocyte preparation is 0.75×10-1.0×10cells/mL, and the content of the cardiomyocytes is higher than 80% while the content of the fibroblasts is not higher than 20%. The cardiomyocyte preparation can improve cardiac ejection fraction and left ventricular fractional shortening, and increase the thickness of the left ventricular inner wall.

Find Patent Forward Citations

Wang, Jiaxian. (2024). Cardiomyocyte preparation and preparation method therefor and use thereof (U.S. Patent No. 12077781). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12077781

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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