The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 03, 2024

Filed:

Dec. 16, 2019
Applicants:

Board of Regents, the University of Texas System, Austin, TX (US);

Consiglio Nazionale Delle Ricerche, Rome, IT;

Inventors:

Gabriel Lopez-Berestein, Houston, TX (US);

Paola Amero, Houston, TX (US);

Cristian Rodriguez-Aguayo, Houston, TX (US);

Rahul Mitra, Houston, TX (US);

Anil K. Sood, Houston, TX (US);

Vittorio De Franciscis, Naples, IT;

David Volk, Houston, TX (US);

Lokesh Ganesh L. Rao, Houston, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/115 (2010.01); A61K 31/337 (2006.01); A61K 33/243 (2019.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); A61K 31/337 (2013.01); A61K 33/243 (2019.01); A61P 35/00 (2018.01); C12N 2310/16 (2013.01); C12N 2310/313 (2013.01); C12N 2310/322 (2013.01); C12N 2310/351 (2013.01); C12N 2310/531 (2013.01); C12N 2320/31 (2013.01); C12N 2320/32 (2013.01);
Abstract

Provided herein are DNA aptamers targeting AXL receptor kinase. The DNA aptamers may comprise a thiophosphate backbone and be chemically modified. Further provided herein are methods of use thereof for the treatment of a disease or disorder, such as cancer.


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