The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 03, 2024

Filed:

Feb. 16, 2023
Applicant:

Terumo Bct, Inc., Lakewood, CO (US);

Inventors:

Nathan D. Frank, Arvada, CO (US);

Brian J. Nankervis, Golden, CO (US);

Dennis J. Hlavinka, Arvada, CO (US);

Thomas G. Dilorenzo, Arvada, CO (US);

Assignee:

Terumo BCT, Inc., Lakewood, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 3/00 (2006.01); B05D 7/00 (2006.01); B05D 7/22 (2006.01); C12M 1/00 (2006.01); C12M 1/12 (2006.01); C12M 1/34 (2006.01); C12M 1/36 (2006.01); C12M 3/04 (2006.01); C12N 5/0775 (2010.01); C12Q 3/00 (2006.01);
U.S. Cl.
CPC ...
C12M 23/20 (2013.01); B05D 7/22 (2013.01); C12M 1/36 (2013.01); C12M 23/50 (2013.01); C12M 25/10 (2013.01); C12M 25/12 (2013.01); C12M 27/10 (2013.01); C12M 29/10 (2013.01); C12M 29/16 (2013.01); C12M 29/18 (2013.01); C12M 41/00 (2013.01); C12M 41/48 (2013.01); C12N 5/0662 (2013.01); C12N 5/0663 (2013.01); C12Q 3/00 (2013.01); B05D 2254/00 (2013.01); B05D 2259/00 (2013.01);
Abstract

Embodiments described herein generally provide for the expansion of cells in a cell expansion system using an active promotion of a coating agent(s) to a cell growth surface in some embodiments. A coating agent may be applied to a surface, such as the cell growth surface of a hollow fiber in a bioreactor, by controlling the movement of a fluid in which a coating agent is suspended, by changing flow rates, by changing flow directions, by rotation of the bioreactor, and/or combinations thereof.


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