The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2024
Filed:
Dec. 19, 2019
Applicants:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Emory University, Atlanta, GA (US);
Inventors:
Eric V. Shusta, Madison, WI (US);
Benjamin Umlauf, Madison, WI (US);
Brantley Herrin, Atlanta, GA (US);
Paul Clark, Madison, WI (US);
John Kuo, Austin, TX (US);
Assignees:
WISCONSIN ALUMNI RESEARCH FOUNDATION, Madison, WI (US);
EMORY UNIVERSITY, Atlanta, GA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); A61K 38/00 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C07K 7/06 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07K 7/06 (2013.01); C12N 15/86 (2013.01); A61K 38/00 (2013.01);
Abstract
The present disclosure provides isolated polypeptides comprising variable lymphocyte receptors that specifically bind the brain extracellular matrix, compositions, and methods of use. Methods of using the variable lymphocyte receptors for the detection and treatment of disease or injury, specifically, for example, cancers including glioblastoma are provided.