The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2024
Filed:
Jun. 30, 2021
Applicant:
Trustees of Tufts College, Medford, MA (US);
Inventor:
Charles B. Shoemaker, Medford, MA (US);
Assignee:
Trustees of Tufts College, Medford, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/12 (2006.01); A61P 31/04 (2006.01); C07K 14/47 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1282 (2013.01); A61P 31/04 (2018.01); C07K 14/47 (2013.01); A61K 2039/505 (2013.01);
Abstract
Polypeptide products, methods, pharmaceutical compositions, and kits are provided for treating a subject exposed to, or at risk for exposure to,microbial pathogens and toxin B produced by(TcdB) pathogens. The methods, compositions and kits include a single domain, anti-TedB VHH polypeptide (antibody), or toxin B binding portion thereof, that specifically binds to and/or neutralizes TedB and treats or prevents illness and disease associated withinfection and TedB intoxication. The anti-TcdB VHHs, or toxin B binding portion thereof, may be recombinantly produced.