The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2024
Filed:
Jun. 03, 2020
Hanping Feng, Ellicott City, MD (US);
Yongrong Zhang, Columbia, MD (US);
Zhiyong Yang, West Friendship, MD (US);
Hua Yu, Columbia, MD (US);
Yifan Zhang, North Potomac, MD (US);
Hanping Feng, Ellicott City, MD (US);
Yongrong Zhang, Columbia, MD (US);
Zhiyong Yang, West Friendship, MD (US);
Hua Yu, Columbia, MD (US);
Yifan Zhang, North Potomac, MD (US);
FZATA, INC., Halethorpe, MD (US);
UNIVERSITY OF MARYLAND, BALTIMORE, Baltimore, MD (US);
Abstract
Novel, antibody-based binding agents derived from camelid VH and human immunoglobulins are described. These binding agents recognize and bind with specificity totoxin A and/or toxin B and in some cases exhibit toxin neutralizing activity. These binding agents can be used to treat or prevent primary and recurrent CDI. The binding agents include humanized VH peptide monomers, linked groups of humanized VH peptide monomers, humanized VH peptide monomers joined to antibody Fc domains, and humanized VH peptide monomers joined to IgG antibodies.