The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2024
Filed:
Sep. 07, 2022
University of Massachusetts, Boston, MA (US);
The Johns Hopkins University, Baltimore, MD (US);
Kennedy Krieger Institute, Inc., Baltimore, MD (US);
Miguel Sena Esteves, Westford, MA (US);
Sourav Roy Choudhury, Newton, MA (US);
Kathryn Rae Wagner, Baltimore, MD (US);
Jennifer Gifford Green, Chelmsford, MA (US);
Ana Rita Batista, West Boylston, MA (US);
University of Massachusetts, Boston, MA (US);
The Johns Hopkins University, Baltimore, MD (US);
Kennedy Krieger Institute, Inc., Baltimore, MD (US);
Abstract
The disclosure relates, in some aspects, to adeno-associated virus capsid proteins isolated from an in vivo library and recombinant adeno-associated viruses (rAAVs) comprising the same. In some aspects, the disclosure relates to isolated nucleic acids encoding AAV capsid proteins isolated from an in vivo library. In some embodiments, rAAVs and compositions described by the disclosure are useful for delivery of one or more transgenes to the muscle-tissue of a subject.