logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12077521 B1

PDFFull Text
Date of Patent:
Sep. 03, 2024

Filed:

Nov. 25, 2020

Pyrazole derivatives as malt1 inhibitors

Applicant:

Janssen Pharmaceutica NV, Beerse, BE;

Inventors:

Tianbao Lu, Churchville, PA (US);

Brett Douglas Allison, San Diego, CA (US);

Joseph Kent Barbay, Flourtown, PA (US);

Peter J. Connolly, New Providence, NJ (US);

Maxwell David Cummings, Ambler, PA (US);

Gaston Diels, Beerse, BE;

James Patrick Edwards, Ambler, PA (US);

Kevin D. Kreutter, Plainsboro, NJ (US);

Ulrike Philippar, Antwerp, BE;

Fang Shen, Fort Washington, NJ (US);

Johannes Wilhelmus John Fitzgerald Thuring, Antwerp, BE;

Tongfei Wu, Hever, BE;

Didier Jean-Claude Berthelot, La Neuville Chant d'Oisel, FR;

Assignee:

Janssen Pharmaceutica NV, Beerse, BE;

Attorney:
Primary Examiner:

Michael B Pallay

Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61P 1/00 (2006.01); A61P 11/06 (2006.01); A61P 19/02 (2006.01); A61P 35/00 (2006.01); A61P 37/00 (2006.01); C07D 401/12 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 491/04 (2006.01); C07D 495/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61P 1/00 (2018.01); A61P 11/06 (2018.01); A61P 19/02 (2018.01); A61P 35/00 (2018.01); A61P 37/00 (2018.01); C07D 401/12 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 491/04 (2013.01); C07D 495/04 (2013.01);
Abstract

Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT1. Such compounds are represented by Formula (I) as follows: wherein R, R, R, R, R, R, R, G, and Gare defined herein.

Find Patent Forward Citations

Loading…