The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2024
Filed:
Sep. 06, 2022
Applicant:
University of Miami, Miami, FL (US);
Inventors:
Anthony J. Capobianco, Miami Beach, FL (US);
Stephan C. Schürer, Coral Gables, FL (US);
Xiaoxia Zhu, Palmetto Bay, FL (US);
Tanya T. Kelley, Miami, FL (US);
Assignee:
University of Miami, Miami, FL (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/54 (2006.01);
U.S. Cl.
CPC ...
C07D 231/54 (2013.01); C12Y 207/00 (2013.01); C12Y 306/01003 (2013.01);
Abstract
Disclosed herein are Notch transcriptional activation complex kinase (“MACK”) inhibitors, and methods for their use in treating or preventing diseases, such as cancer. The inhibitors described herein include compounds of Formula (Ia) and pharmaceutically acceptable salts thereof: wherein the substituents are as described.