The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2024
Filed:
Feb. 01, 2021
Applicant:
C4 Therapeutics, Inc., Watertown, MA (US);
Inventors:
Andrew J. Phillips, Arlington, VA (US);
Christopher G. Nasveschuk, Syoneham, MA (US);
James A. Henderson, Weston, MA (US);
Yanke Liang, Brookline, MA (US);
Mark E. Fitzgerald, Watertown, MA (US);
Minsheng He, Watertown, MA (US);
Ryan E. Michael, Newton, MA (US);
Assignee:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/54 (2017.01); A61K 31/4035 (2006.01); A61K 31/438 (2006.01); A61K 31/439 (2006.01); A61K 31/454 (2006.01); A61K 31/547 (2006.01); A61K 31/55 (2006.01); C07D 401/04 (2006.01); C07D 403/04 (2006.01);
U.S. Cl.
CPC ...
A61K 47/545 (2017.08); A61K 31/4035 (2013.01); A61K 31/438 (2013.01); A61K 31/439 (2013.01); A61K 31/454 (2013.01); A61K 31/547 (2013.01); A61K 31/55 (2013.01); A61K 47/554 (2017.08); C07D 403/04 (2013.01);
Abstract
This invention provides heterocyclic compounds that bind to E3 Ubiquitin Ligase (typically through cereblon) ('Degrons'), which can be used as is or linked to a Targeting Ligand for a selected Target Protein for therapeutic purposes and methods of use and compositions thereof as well as methods for their preparation.