The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2024

Filed:

Jul. 23, 2020
Applicants:

The Regents of the University of California, Oakland, CA (US);

University of Florida Research Foundation, Incorporated, Gainesville, FL (US);

Inventors:

Steven Conolly, Walnut Creek, CA (US);

Carlos Rinaldi, Gainesville, FL (US);

Bo Zheng, Seattle, WA (US);

Prashant Chandrasekharan, Berkeley, CA (US);

Daniel Hensley, Emeryville, CA (US);

Shehaab Savliwala, Gainesville, FL (US);

Zhi Wei Tay, Singapore, SG;

Rohan Deepak Dhavalikar, Hillsboro, OR (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01R 33/12 (2006.01); A61B 5/0515 (2021.01);
U.S. Cl.
CPC ...
G01R 33/1276 (2013.01); A61B 5/0515 (2013.01);
Abstract

A magnetic particle imaging system that includes a magnetic field generating system with at least one magnet and providing a gradient magnetic field within an observation region such that the gradient magnetic field has a dynamic field-free region (FFR) for an object under observation having strongly-interacting magnetic particles distributed therein. The magnetic field generating system also includes a drive field and a slow shift field that dynamically shifts the FFR across a field of view (FOV) within the observation region, where the trajectory of the drive field accommodates for a coercivity of the strongly-interacting magnetic particles by ensuring that the particles in the FOV are saturated to a full coercivity field prior to traversing to an opposite-polarity of coercivity. The magnetic particle imaging system also includes a detection system proximate the observation region and configured to detect a signal from the strongly-interacting magnetic particles. The magnetic particle imaging system further includes signal processor in communication with the detection system, configured to receive and process the detected signal to remove a coercivity shift due to the coercivity of the strongly-interacting magnetic particles, and convert the processed detection signal into an image of the strongly-interacting magnetic particles.


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