The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2024

Filed:

May. 31, 2019
Applicant:

Mogam Institute for Biomedical Research, Gyeonggi-do, KR;

Inventors:

Dong-Sik Kim, Gyeonggi-do, KR;

Mi Jung Lee, Gyeonggi-do, KR;

Mi Young Oh, Gyeonggi-do, KR;

Hye-Ji Choi, Gyeonggi-do, KR;

Gil-Jung Kim, Gyeonggi-do, KR;

Shin A Jang, Gyeonggi-do, KR;

Ae Rin Yoon, Gyeonggi-do, KR;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C40B 40/10 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C40B 40/10 (2013.01); C07K 16/005 (2013.01); C07K 16/28 (2013.01); C12N 15/1037 (2013.01); C07K 2317/40 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/94 (2013.01);
Abstract

The present invention relates to a novel antibody library and an antibody-screening method using same. Having a human sequence-derived specific VH or VL scaffold, the antibody library according to the present invention exhibits high thermodynamic stability and enjoys the advantages of allowing high soluble expression as well as reversible folding. In addition, the antibody according to the present invention includes a variety of rationally controlled CDRs so as to exhibit high specificity and high affinity to all antigens and thus can be advantageously used for selecting an adequate candidate antibody against a target antigen.


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