The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2024
Filed:
Dec. 07, 2017
Merck Sharp & Dohme Llc, Rahway, NJ (US);
Beijing Genomics Institute AT Shenzhen, Guangdong, CN;
Peter M. Shaw, Yardley, PA (US);
Devan V. Mehrotra, Lansdale, PA (US);
Rebecca L. Blanchard, Allentown, PA (US);
Judong Shen, Westfield, NJ (US);
Robin Mogg, Chalfont, PA (US);
Mary Beth Dorr, Collegeville, PA (US);
Junhua Li, Shenzhen, CN;
Xun Xu, Shenzhen, CN;
Merck Sharp & Dohme LLC, Rahway, NJ (US);
Beijing Genomics Institute at Shenzhen, Shenzhen, CN;
Abstract
The present invention provides genetic markers on human chromosome 6 that are associated with a beneficial response to a treatment that targets() toxin B (TcdB), e.g. a TcdB antibody. These TcdB treatment response markers are useful, inter alia, to identify patients who are most likely to benefit from treatment that targets TcdB in methods of treating patients having a disease susceptible to treatment with a TcdB antibody, and in methods for selecting the most appropriate therapy for such patients. The invention also provides antibodies, drug products, and kits useful with the TcdB Treatment response markers of the invention.