The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2024

Filed:

Oct. 05, 2015
Applicants:

Assistance Publique-hopitaux DE Paris, Paris, FR;

Fondation Imagine-institut Des Maladies Genetiques, Paris, FR;

Universtie Paris Descartes, Paris, FR;

Institut National DE LA Sante ET DE LA Recherche Medicale (Inserm), Paris, FR;

Inventors:

Marina Cavazzana, Paris, FR;

Isabelle André, Meudon, FR;

Chantal Lagresle-Peyrou, Montrouge, FR;

Salima Hacein-Bey-Abina, La Garenne Colombes, FR;

Christian Reimann, Freiburg, DE;

Corinne De Chappedelaine, Paris, FR;

Emmanuelle Six, Saint Geneviève des Bois, FR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0636 (2013.01); C12N 2501/42 (2013.01); C12N 2502/1114 (2013.01); C12N 2506/11 (2013.01); C12N 2533/50 (2013.01); C12N 2533/52 (2013.01);
Abstract

The invention relates to the field of cell therapy and to an in vitro method for generating T-cell progenitors, comprising the step of exposing CD34+ cells in a medium containing a Notch ligand, a soluble domain of the Delta-like ligand 4, joined to an Fc region of a protein IgG, in the presence of a fragment of fibronectin comprising the motifs RGDS and CS-1 and a heparin-binding domain.


Find Patent Forward Citations

Cavazzana, Marina. (2024). Method for generating t-cell progenitors (U.S. Patent No. 12071635). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12071635

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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