The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2024
Filed:
Apr. 23, 2019
Applicant:
The United States of America,as Represented BY the Secretary,department of Health and Human Services, Bethesda, MD (US);
Inventors:
Shirin Munir, Potomac, MD (US);
Linda G. Brock, Wyckoff, NJ (US);
Ursula J. Buchholz, Silver Spring, MD (US);
Peter L. Collins, Silver Spring, MD (US);
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); A61K 39/155 (2006.01); A61P 31/14 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61K 39/155 (2013.01); A61P 31/14 (2018.01); A61K 2039/5256 (2013.01); A61K 2039/543 (2013.01); C12N 2760/18534 (2013.01); C12N 2760/18544 (2013.01); C12N 2760/18551 (2013.01);
Abstract
Disclosed are live, chimeric non-human Mononegavirales vectors that allow a cell to express at least one protein from at least one human pathogen. In addition, compositions comprising the vectors, methods and kits for eliciting an immune response in a host, and methods of making the vectors are disclosed, in accordance with embodiments of the invention.