The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2024
Filed:
Aug. 30, 2023
Applicant:
Akouos, Inc., Boston, MA (US);
Inventors:
Emmanuel John Simons, Brookline, MA (US);
Ellen Reisinger, Dußlingen, DE;
Sebastian Kügler, Göttingen, DE;
Hanan Al-Moyed, Göttingen, DE;
Assignee:
Akouos, Inc., Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); A01K 67/0276 (2024.01); A61K 38/17 (2006.01); A61K 48/00 (2006.01); A61P 27/16 (2006.01); C07K 14/47 (2006.01); C12N 5/0793 (2010.01); C12N 9/16 (2006.01); C12N 15/52 (2006.01); C12N 15/65 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12N 15/52 (2013.01); A01K 67/0276 (2013.01); A61K 38/1709 (2013.01); A61K 48/0075 (2013.01); A61P 27/16 (2018.01); C07K 14/47 (2013.01); C12N 5/062 (2013.01); C12N 9/16 (2013.01); C12N 15/65 (2013.01); C12N 15/86 (2013.01); C12N 15/902 (2013.01); A01K 2217/075 (2013.01); A01K 2227/103 (2013.01); A01K 2267/03 (2013.01); C12N 2310/20 (2017.05); C12N 2750/14143 (2013.01); C12N 2830/008 (2013.01); C12Y 301/03001 (2013.01);
Abstract
Provided herein are compositions that include at least two different nucleic acid vectors, where each of the at least two different vectors includes a coding sequence that encodes a different portion of an otoferlin protein, and the use of these compositions to treat hearing loss in a subject.