The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2024
Filed:
Sep. 04, 2019
Osaka University, Suita, JP;
National Institutes of Biomedical Innovation, Health and Nutrition, Ibaraki, JP;
National University Corporation Kobe University, Kobe, JP;
Akira Kikuchi, Suita, JP;
Shinji Matsumoto, Suita, JP;
Satoshi Obika, Ibaraki, JP;
Yuya Kasahara, Ibaraki, JP;
Takumi Fukumoto, Kobe, JP;
Osaka University, Osaka, JP;
National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, JP;
National University Corporation Kobe University, Hyogo, JP;
Abstract
The purpose of the present invention is to provide an antisense oligonucleotide that targets an ARL4C molecule and exerts an antitumor effect in vivo, and a nucleic acid drug using the antisense oligonucleotide. An antisense oligonucleotide that has a base sequence consisting of at least 10 consecutive bases contained in the base sequence represented by SEQ ID NO: 1. This antisense oligonucleotide targets an ARL4C molecule and thus can inhibit the expression of ARL4C in a tumor cell in vitro and suppress the migration and proliferation thereof. When systemically administered, moreover, the antisense oligonucleotide can exert an excellent antitumor effect in vivo too.