The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2024
Filed:
Sep. 27, 2021
Applicant:
Gen-probe Incorporated, San Diego, CA (US);
Inventors:
Kui Gao, San Diego, CA (US);
Jijumon Chelliserry, San Diego, CA (US);
Jeffrey Linnen, Poway, CA (US);
Assignee:
Gen-Probe Incorporated, San Diego, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C12Q 1/6806 (2018.01); C12Q 1/70 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1003 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/70 (2013.01); Y02A 50/30 (2018.01);
Abstract
Disclosed herein are lysis reagents for lysing red blood cells, thereby releasing an analyte, such as RNA from a host or pathogen, in a form suitable for analysis. The reagent includes at least a buffer, a detergent and one or both of a chloride containing salt and an anti-coagulant. The reagent serves to lyse blood cells, protect the released analyte from degradation in the lysate, and is compatible with subsequent steps for analysis of the analyte such as target capture, amplification, detection, or sequencing.