The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2024
Filed:
Mar. 16, 2020
The Trustees of Dartmouth College, Hanover, NH (US);
King's College London, London, GB;
Randolph J. Noelle, Plainfield, NH (US);
Sabrina Ceeraz, Lebanon, NH (US);
Isabelle LeMercier, Enfield, NH (US);
Elizabeth Nowak, West Lebanon, NH (US);
Janet Lines, London, GB;
THE TRUSTEES OF DARMOUTH COLLEGE, Hanover, NH (US);
KING'S COLLEGE LONDON, London, GB;
Abstract
The present invention relates to a fusion proteins comprising regulatory T cell protein, VISTA (V-domain Immunoglobulin Suppressor of T cell Activation (PD-L3) and an immunoglobulin protein (Ig). The invention also provides the use of VISTA polypeptides, multimeric VISTA polypeptides, VISTA-conjugates (e.g., VISTA-Ig), and VISTA antagonists for the treatment of autoimmune disease, allergy, and inflammatory conditions.