The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2024

Filed:

Oct. 28, 2022
Applicant:

Arcus Biosciences, Inc., Hayward, CA (US);

Inventors:

Joel Worley Beatty, San Mateo, CA (US);

Samuel Lawrie Drew, Millbrae, CA (US);

Matthew Epplin, San Francisco, CA (US);

Jeremy Fournier, Fremont, CA (US);

Balint Gal, Hayward, CA (US);

Clayton Hardman, San Francisco, CA (US);

Artur Karenovich Mailyan, Livermore, CA (US);

Kenneth Victor Lawson, San Francisco, CA (US);

Manmohan Reddy Leleti, Dublin, CA (US);

Dongdong Liu, Fremont, CA (US);

Guillaume Mata, Berkeley, CA (US);

Ma{hacek over (s)}a Podunavac, Hayward, CA (US);

Jay Patrick Powers, Sisters, OR (US);

Brandon Reid Rosen, San Mateo, CA (US);

Kai Yu, Hayward, CA (US);

Assignee:

Arcus Biosciences, Inc., Hayward, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/56 (2006.01); C07D 405/04 (2006.01); C07D 405/06 (2006.01); C07D 409/04 (2006.01); C07D 409/06 (2006.01); C07D 413/06 (2006.01);
U.S. Cl.
CPC ...
C07D 231/56 (2013.01); C07D 405/04 (2013.01); C07D 405/06 (2013.01); C07D 409/04 (2013.01); C07D 409/06 (2013.01); C07D 413/06 (2013.01);
Abstract

The present disclosure is directed to compounds that are inhibitors of HIF-2α having a structure according to Formula I, and compositions containing those compounds. Methods of using the compounds for the treatment of diseases, disorders, or conditions are also described.


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