The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2024

Filed:

Mar. 07, 2019
Applicants:

Carl Genberg, Las Vegas, NV (US);

Paul B. Savage, Mapleton, UT (US);

Inventors:

Carl Genberg, Las Vegas, NV (US);

Paul B. Savage, Mapleton, UT (US);

Assignee:

Brigham Young University, Provo, UT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/56 (2006.01); A61K 47/10 (2017.01);
U.S. Cl.
CPC ...
A61K 31/56 (2013.01); A61K 47/10 (2013.01);
Abstract

The present disclosure describes treatment compositions and methods for preventing and/or treating microbial infections of ciliated tissues, such as tissues of the trachea, lungs, and sinuses. The method utilizes a treatment composition that includes a cationic steroidal antimicrobial (CSA) compound, a poloxamer, and a carrier, which is administered to ciliated tissue, such as lung tissue, in order to prevent or treat a microbial infection by killing microbes associated with the ciliated tissue. The poloxamer forms micelles that encapsulate the CSA compound, the poloxamer being included in the treatment composition in an amount, by weight, that is about 100 to 1000 times the amount of the CSA compound.


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