The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2024

Filed:

Mar. 13, 2019
Applicant:

The Uab Research Foundation, Birmingham, AL (US);

Inventors:

Massimo Antonio Fazio, Birmingham, AL (US);

Christopher Anthony Girkin, Mountain Brook, AL (US);

Assignee:

THE UAB RESEARCH FOUNDATION, Birmingham, AL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 3/12 (2006.01); A61B 3/00 (2006.01); A61B 3/10 (2006.01); A61B 3/16 (2006.01); G06T 7/00 (2017.01); A61B 8/10 (2006.01);
U.S. Cl.
CPC ...
A61B 3/1233 (2013.01); A61B 3/0025 (2013.01); A61B 3/102 (2013.01); A61B 3/1241 (2013.01); A61B 3/165 (2013.01); G06T 7/0016 (2013.01); A61B 8/10 (2013.01); G06T 2207/10101 (2013.01); G06T 2207/30041 (2013.01); G06T 2207/30104 (2013.01);
Abstract

Relationships between morphological changes to an eye due to intraocular pressure changes and blood perfusion changes in the retina are determined by colocalizing retinal perfusion data and optic nerve head (ONH) mechanical deformation data. Perfusion changes from intraocular pressure (IOP) changes are determined by colocalizing retinal perfusion data with ONH mechanical deformation data. Optical coherence tomography-angiography (OCT-A) can be used to generate both retinal perfusion data and mechanical deformation data for an imaged volume. A three-dimensional model (e.g., connectivity map or connectivity model) of the vasculature can be generated from the OCT-A imaging data and used to predict changes in blood perfusion in various areas of the retina due to IOP-induced mechanical deformations.


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