The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2024

Filed:

Jan. 25, 2018
Applicants:

Whitehead Institute for Biomedical Research, Cambridge, MA (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

Vikram Khurana, Cambridge, MA (US);

Chee Yeun Chung, Cambridge, MA (US);

Susan Lindquist, Brookline, MA (US);

Bonnie A. Berger, Newtonville, MA (US);

Ernest Fraenkel, Newton, MA (US);

Jian Peng, Champaign, IL (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01); C12Q 1/02 (2006.01); G01N 33/50 (2006.01); G16B 5/00 (2019.01); G16B 25/00 (2019.01); G16B 30/10 (2019.01);
U.S. Cl.
CPC ...
G16B 5/00 (2019.02); C12Q 1/025 (2013.01); G01N 33/5058 (2013.01); G16B 25/00 (2019.02); G16B 30/10 (2019.02); G01N 2500/10 (2013.01);
Abstract

Disclosed are methods, systems, cells and compositions directed to modeling a physiologic or pathologic process in an animal using a set of yeast genes analogous to a set of animal genes and augmenting the physiologic or pathologic process in the animal with predicted gene interactions based on the interactions between the set of yeast genes. Also disclosed are methods of screening for and using therapeutics for neurodegenerative proteinopathies.


Find Patent Forward Citations

Loading…