The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2024

Filed:

Aug. 03, 2018
Applicant:

The Trustees of Columbia University IN the City of New York, New York, NY (US);

Inventors:

Wei Min, Fort Lee, NJ (US);

Fanghao Hu, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/65 (2006.01); C12Q 1/6816 (2018.01); C12Q 1/6827 (2018.01); C12Q 1/6834 (2018.01); C12Q 1/686 (2018.01); B82Y 15/00 (2011.01); B82Y 30/00 (2011.01); H04Q 11/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6816 (2013.01); C12Q 1/6827 (2013.01); C12Q 1/6834 (2013.01); C12Q 1/686 (2013.01); G01N 21/65 (2013.01); B82Y 15/00 (2013.01); B82Y 30/00 (2013.01); C12Q 2565/632 (2013.01); H04Q 11/0005 (2013.01);
Abstract

A method for optical super-multiplexing using polyynes to provide enhanced images from stimulated Raman microscopy is disclosed. In some exemplary embodiments, the polyynes are organelle-targeted or spectral barcoded. Imaging can be enhanced by using the polyynes to image whole live cells or specific organelles within live cells. The polyynes can also be used in optical data storage (i.e., encoding) and identification (i.e., decoding) applications.


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