The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2024

Filed:

Jul. 13, 2022
Applicant:

Chigenovo Co., Ltd, Beijing, CN;

Inventors:

Liping Yang, Beijing, CN;

Shaohong Chen, Beijing, CN;

Ruixuan Jia, Beijing, CN;

Fan Zhang, Beijing, CN;

Saichao He, Beijing, CN;

Tianyong Shi, Beijing, CN;

Dandan Hao, Beijing, CN;

Hongjie Pei, Beijing, CN;

Luying Zeng, Beijing, CN;

Assignee:

CHIGENOVO CO., LTD, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); A61K 48/00 (2006.01); A61P 27/02 (2006.01); C12N 9/02 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61P 27/02 (2018.01); C12N 9/0071 (2013.01); A61K 48/00 (2013.01); C12N 2750/14143 (2013.01);
Abstract

The present application relates to a vector comprising a polynucleotide encoding CYP4V2 and a promoter operably linked to the polynucleotide encoding CYP4V2. The vector described herein has a good expression effect, high expression speed, and more stable expression intensity. The present application also provides cells, pharmaceutical compositions, and kits comprising the vector, and methods for treating, alleviating, and/or preventing a disease or disorder associated with retinal pigment epithelium (RPE) atrophy.


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