The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 20, 2024
Filed:
Feb. 18, 2020
Applicant:
Sigma-aldrich Co. Llc, St. Louis, MO (US);
Inventors:
Fuqiang Chen, St. Louis, MO (US);
Xiao Ding, St. Louis, MO (US);
Yongmei Feng, St. Louis, MO (US);
Gregory Davis, Webster Groves, MO (US);
Assignee:
Sigma-Aldrich Co. LLC, St. Louis, MO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); C12N 15/10 (2006.01); C12N 15/113 (2010.01); C12N 15/85 (2006.01); C12N 15/90 (2006.01); C12Q 1/6897 (2018.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/102 (2013.01); C12N 9/22 (2013.01); C12N 15/113 (2013.01); C12N 15/85 (2013.01); C12N 15/907 (2013.01); C12Q 1/6897 (2013.01); A61K 48/005 (2013.01); C07K 2319/09 (2013.01); C07K 2319/10 (2013.01); C07K 2319/80 (2013.01); C07K 2319/81 (2013.01); C12N 2310/20 (2017.05); C12N 2800/80 (2013.01);
Abstract
Compositions and methods for using nucleosome interacting protein domains to increase accessibility of programmable DNA modification proteins to target chromosomal sequences, thereby increasing efficiency of targeted genome/epigenetic modification in eukaryotic cells.