The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 20, 2024
Filed:
Jun. 01, 2021
Applicant:
University of Kentucky Research Foundation, Lexington, KY (US);
Inventors:
Chang-Guo Zhan, Lexington, KY (US);
Fang Zheng, Lexington, KY (US);
Chunhui Zhang, Lexington, KY (US);
Assignee:
University of Kentucky Research Foundation, Lexington, KY (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/44 (2006.01); G01N 33/94 (2006.01); G16B 15/30 (2019.01); G16B 30/10 (2019.01);
U.S. Cl.
CPC ...
C07K 16/44 (2013.01); G01N 33/9486 (2013.01); G16B 15/30 (2019.02); G16B 30/10 (2019.02); C07K 2317/24 (2013.01);
Abstract
Compositions and methods are provided for use in binding opioids, such as 6-MAM, morphine, heroin, hydrocodone, oxycodone, meperidine, and fentanyl, while avoiding binding to OUD treatment agents, such as naloxone and naltrexone. Methods are also provided for use in a systematic structure-based virtual screening and design approach for identification of such antibodies. Methods are also provided for use in treating OUD. Methods are also provided for use in detecting an opioid in a sample.