The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 20, 2024
Filed:
Nov. 01, 2019
Achillion Pharmaceuticals, Inc., Blue Bell, PA (US);
Jason Allan Wiles, Madison, CT (US);
Venkat Rao Gadhachanda, Hamden, CT (US);
Qiuping Wang, Bethany, CT (US);
Godwin Pais, Hamden, CT (US);
Akihiro Hashimoto, Branford, CT (US);
Dawei Chen, Guilford, CT (US);
Xiangzhu Wang, Branford, CT (US);
Atul Agarwal, Hamden, CT (US);
Milind Deshpande, Madison, CT (US);
Avinash S. Phadke, Branford, CT (US);
Achillion Pharmaceuticals, Inc., Boston, MA (US);
Abstract
Compounds, methods of use, and processes for making inhibitors of complement factor D comprising Formula I, or a pharmaceutically acceptable salt or composition thereof wherein Ror Ron the A group is an aryl, heteroaryl or heterocycle (R) are provided. The inhibitors described herein target factor D and inhibit or regulate the complement cascade at an early and essential point in the alternative complement pathway, and reduce factor D's ability to modulate the classical and lectin complement pathways. The inhibitors of factor D described herein are capable of reducing the excessive activation of complement, which has been linked to certain autoimmune, inflammatory, and neurodegenerative diseases, as well as ischemia-reperfusion injury and cancer.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile