The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 20, 2024
Filed:
Nov. 03, 2023
Virginia Commonwealth University, Richmond, VA (US);
Iiiexcor Holdings, Llc, Henrico, VA (US);
King Abdulaziz University, Jeddah, SA;
Children's Hospital of Philadelphia (Chop), Philadelphia, PA (US);
Martin Safo, Richmond, VA (US);
Yan Zhang, Glen Allen, VA (US);
Andrew Fleischman, Henrico, VA (US);
David Light, Henrico, VA (US);
Moustafa El-Araby, Jeddah, SA;
Abdelsattar Omar, Jeddah, SA;
Osheiza Abdulmalik, Philadelphia, PA (US);
VIRGINIA COMMONWEALTH UNIVERISTY, Richmond, VA (US);
KING ABDULAZIZ UNIVERSITY, Jeddah, SA;
CHILDREN'S HOSPITAL OF PHILADELPHIA (CHOP), Philadelphia, PA (US);
ILLEXCOR HOLDINGS, LLC, Henrico, VA (US);
Abstract
Compounds and methods for preventing and/or treating one or more symptoms of sickle cell diseases (SCD) by administering at least one of the compounds are provided. The compounds are chemically modified to increase bioavailability and activity, e.g., so that the compounds prevent adhesion and sickling of red blood cells (RBCs).