The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2024

Filed:

Dec. 05, 2022
Applicant:

Bio-rad Laboratories, Inc., Hercules, CA (US);

Inventors:

Kalyan Handique, Hercules, CA (US);

Ronald Lebofsky, Hercules, CA (US);

Assignee:

Bio-Rad Laboratories, Inc., Hercules, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); B01L 7/00 (2006.01); C12Q 1/686 (2018.01);
U.S. Cl.
CPC ...
B01L 3/50255 (2013.01); B01L 7/52 (2013.01); C12Q 1/686 (2013.01); B01L 2200/021 (2013.01); B01L 2200/026 (2013.01); B01L 2200/0652 (2013.01); B01L 2200/0689 (2013.01); B01L 2300/041 (2013.01); B01L 2300/046 (2013.01); B01L 2300/069 (2013.01); B01L 2300/0819 (2013.01); B01L 2300/0893 (2013.01); B01L 2300/168 (2013.01); B01L 2300/18 (2013.01); B01L 2300/1816 (2013.01);
Abstract

The invention(s) cover systems and methods for target detection in a multiplexed and rapid manner. Embodiments of the system can include: a base substrate; and an array of sample processing regions defined at a broad surface of the base substrate, wherein each of the array of sample processing regions includes: a set of microwell subarrays arranged in a gradient by volumetric capacity between an upstream end and a downstream end of each respective sample processing region, and a boundary separating each respective sample processing region from adjacent sample processing regions. The system can support methods, with example implementation by an automated platform, for returning preliminary results from a subset of microwells of the samples processing regions, as well as results pertaining to specific and non-specific amplification, for multiple targets of a sample.


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