The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2024

Filed:

May. 03, 2017
Applicants:

Consiglio Nazionale Delle Ricerche, Rome, IT;

Plasma Diagnostics and Technologies S.r.l., Pisa, IT;

Universita Degli Studi Di Firenze, Florence, IT;

Inventors:

Angela Zoppi, Florence, IT;

Mario Del Rosso, Pistoia, IT;

Anna Laurenzana, Tricarico, IT;

Gabriella Fibbi, Florence, IT;

Francesca Margheri, Empoli, IT;

Anastasia Chilla', Florence, IT;

Giancarlo Margheri, Rome, IT;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 33/242 (2019.01); A61K 35/28 (2015.01); A61K 41/00 (2020.01); A61K 47/69 (2017.01); A61K 49/00 (2006.01); A61K 51/12 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 51/1203 (2013.01); A61K 33/242 (2019.01); A61K 35/28 (2013.01); A61K 41/0052 (2013.01); A61K 47/6901 (2017.08); A61K 49/0065 (2013.01); A61P 35/00 (2018.01);
Abstract

The present invention refers to cells from a subpopulation of progenitors of endothelial cells loaded with gold nanoparticles sensitive to excitation with infrared radiation with consequent release of thermal energy, to a composition having a plurality of these cells and to their use in the diagnosis and treatment of solid tumours thanks to the selective localization of the composition in the tumour mass, which can be thus identified easily for diagnostic purposes by marking the cells with appropriate marking agents, or treated by stimulation with pulsed laser beam up to the complete cauterization of the tumour mass for a targeted and highly effective therapeutic action.


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