The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2024

Filed:

Jun. 17, 2022
Applicant:

Avidity Biosciences, Inc., San Diego, CA (US);

Inventors:

Arthur A. Levin, Del Mar, CA (US);

Andrew John Geall, Carlsbad, CA (US);

Venkata Ramana Doppalapudi, San Diego, CA (US);

Michael Caramian Cochran, La Jolla, CA (US);

Hanhua Huang, San Diego, CA (US);

Rob Burke, Encinitas, CA (US);

Assignee:

AVIDITY BIOSCIENCES, INC., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); A61K 31/7088 (2006.01); A61K 31/713 (2006.01); A61K 47/60 (2017.01); A61K 47/64 (2017.01); A61K 47/68 (2017.01); A61K 48/00 (2006.01); A61P 21/00 (2006.01); C07K 14/00 (2006.01); C07K 16/28 (2006.01); C07K 16/40 (2006.01); C12N 15/113 (2010.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6803 (2017.08); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 47/60 (2017.08); A61K 47/6455 (2017.08); A61K 47/6807 (2017.08); A61K 47/6849 (2017.08); A61K 48/0058 (2013.01); A61K 48/0066 (2013.01); A61K 48/0083 (2013.01); A61P 21/00 (2018.01); C07K 14/003 (2013.01); C07K 16/2881 (2013.01); C07K 16/40 (2013.01); C12N 15/113 (2013.01); A61K 38/00 (2013.01); C12N 2310/11 (2013.01); C12N 2310/315 (2013.01); C12N 2310/3233 (2013.01); C12N 2310/3513 (2013.01); C12N 2320/32 (2013.01); C12N 2320/33 (2013.01);
Abstract

Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.


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