The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2024

Filed:

Aug. 07, 2020
Applicant:

Wayne State University, Detroit, MI (US);

Inventor:

Jian-Ping Jin, Chicago, IL (US);

Assignee:

Wayne State University, Detroit, MI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); A61K 38/17 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1719 (2013.01); G01N 33/6887 (2013.01); G01N 2333/4712 (2013.01); G01N 2800/324 (2013.01); G01N 2800/325 (2013.01);
Abstract

Methods and compositions for treating a disorder of cardiac muscle and/or skeletal muscle in a subject according to aspects of the present disclosure. Treatment methods include administering a therapeutically effective dose of a C-terminal portion of troponin I capable of reducing sensitivity of cardiac muscle and/or skeletal muscle to Cawithout decreasing maximum force production. Assays for identification of compounds capable of reducing sensitivity of cardiac muscle and/or skeletal muscle to Cawithout decreasing maximum force production are further provided.


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Jin, Jian-Ping. (2024). Compositions and methods relating to a c-terminal peptide of troponin i with activity as a myofilament ca2+ desensitizer (U.S. Patent No. 12064468). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12064468

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