The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2024

Filed:

Feb. 26, 2021
Applicants:

King's College London, London, GB;

The Trustees of Dartmouth College, Hanover, NH (US);

Inventors:

Randolph J. Noelle, Plainfield, NH (US);

Sabrina Ceeraz, Lebanon, NH (US);

Isabelle Lemercier, Enfield, NH (US);

Elizabeth Nowak, West Lebanon, NH (US);

Janet Lines, London, GB;

Li Wang, Norwich, VT (US);

Mark Spaller, Lebanon, NH (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/00 (2006.01); A61K 9/00 (2006.01); A61K 38/10 (2006.01); A61K 39/00 (2006.01); A61K 45/06 (2006.01); C07K 7/08 (2006.01); C07K 16/28 (2006.01); G01N 33/566 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/10 (2013.01); A61K 9/0019 (2013.01); A61K 39/0005 (2013.01); A61K 45/06 (2013.01); C07K 7/08 (2013.01); C07K 16/2827 (2013.01); G01N 33/566 (2013.01); A61K 38/00 (2013.01); C07K 2317/74 (2013.01); C07K 2317/76 (2013.01); C07K 2319/30 (2013.01); Y02A 50/30 (2018.01);
Abstract

The present invention is directed to a peptide, multimer, conjugate, analog, derivative or mimetic thereof that inhibits the activity of VISTA. The invention further contemplates therapeutic use of the VISTA antagonist peptide, multimer, conjugate, derivative or mimetic thereof, including treating or preventing cancer, bacterial infections, viral infections, parasitic infections and fungal infections, as well as research uses of the antagonist.


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