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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12064453 B1

PDFFull Text
Date of Patent:
Aug. 20, 2024

Filed:

Sep. 26, 2018

Biochemical and biomechanical conditioning for enhancing personalized mesenchymal stem cell therapies

Applicant:

Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Aaron B. Baker, Austin, TX (US);

Jason Lee, Austin, TX (US);

Assignee:

Board of Regents, The University of Texas System, Austin, TX (US);

Attorney:

Parker Highlander PLLC

Primary Examiner:

Teresa E Knight

Int. Cl.
CPC ...
A61K 35/28 (2015.01); A61K 9/00 (2006.01); A61P 9/10 (2006.01); C12N 5/071 (2010.01); C12N 5/0775 (2010.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A61K 9/0019 (2013.01); A61K 9/0024 (2013.01); A61P 9/10 (2018.01); C12N 5/0668 (2013.01); C12N 5/069 (2013.01); A61K 2035/124 (2013.01); C12N 2501/999 (2013.01); C12N 2527/00 (2013.01);
Abstract

A high-throughput screening system is provided for optimizing the conditioning of patient-specific mesenchymal stem cells using a combinatorial set of biochemical factors, pharmacological inhibitors, and biomechanical forces. Also provided are generalized conditions for performing such conditioning. Cells made by these methods are also provided, in addition to cells having a mixed endothelial cell/pericyte phenotype. These cells produce angiogenic growth factors and induce vascularization following implantation.

Find Patent Forward Citations

Baker, Aaron. (2024). Biochemical and biomechanical conditioning for enhancing personalized mesenchymal stem cell therapies (U.S. Patent No. 12064453). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12064453

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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