The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2024

Filed:

May. 21, 2021
Applicants:

The Children's Medical Center Corporation, Boston, MA (US);

The General Hospital Corporation, Boston, MA (US);

Inventors:

Umut Ozcan, Boston, MA (US);

Joseph Majzoub, Boston, MA (US);

Ralph Mazitschek, Belmont, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/198 (2006.01); A61K 31/19 (2006.01); A61K 31/192 (2006.01); A61K 31/194 (2006.01); A61K 31/195 (2006.01); A61K 38/22 (2006.01); A61K 45/06 (2006.01); A61P 3/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/198 (2013.01); A61K 31/19 (2013.01); A61K 31/192 (2013.01); A61K 31/194 (2013.01); A61K 31/195 (2013.01); A61K 38/2264 (2013.01); A61K 45/06 (2013.01); A61P 3/04 (2018.01);
Abstract

Pentacyclic triterpene weight loss agents are provided herein. Also provided are pharmaceutical formulations containing a therapeutically effective amount of one or more of the weight loss agents, or pharmaceutically acceptable salts or prodrugs thereof, in combination with one or more pharmaceutically acceptable excipients. The pharmaceutical formulations can be administered to a pre-obese, obese, or morbidly obese patient to induce weight loss, reduce body fat, reduce food intake, improve glucose homeostasis, prevent obesity, or a combination thereof. The weight loss agents can also be co-administered with leptin or a leptin analog.


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