The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 13, 2024

Filed:

Jan. 27, 2021
Applicant:

The Trustees of Columbia University IN the City of New York, New York, NY (US);

Inventors:

Wei Min, Fort Lee, NJ (US);

Lingyan Shi, Brooklyn, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G16H 20/10 (2018.01); A61K 49/00 (2006.01); G01N 21/65 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G16H 20/10 (2018.01); A61K 49/0002 (2013.01); A61K 49/0004 (2013.01); G01N 21/65 (2013.01); G01N 33/6848 (2013.01); G01N 2021/656 (2013.01); G01N 2458/15 (2013.01); G01N 2500/10 (2013.01); G01N 2570/00 (2013.01);
Abstract

Incorporation of deuterium into the lipids, proteins, and/or genetic material in cells, tissues, organs, or organisms, including animals, such as humans, and plants, by administration of heavy water, allows for the spectral determination of levels of lipids, proteins, and/or genetic material using Raman spectroscopy, such as stimulated Raman spectroscopy. Following administration of a drug, changes in the relative amounts of lipid, protein, and/or genetic materials can be determined, and the efficacy, or lack thereof, of the administered drug can be determined.


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