The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2024
Filed:
Apr. 30, 2019
Inv Nylon Chemicals Americas, Llc, Wilmington, DE (US);
Alexander Brett Foster, Redcar, GB;
Cristina Serrano Amatriain, Redcar, GB;
Gary J. Smith, Redcar, GB;
Paul Sheldon Pearlman, Thornton, PA (US);
Mark Paul Taylor, Redcar, GB;
Jonathan Combe, Redcar, GB;
Daniel Bawdon, Redcar, GB;
INV NYLON CHEMICALS AMERICAS, LLC, Wilmington, DE (US);
Abstract
Provided herein are methods for increasing the yield of an extracellular product synthesized by an organism cultured in a continuous aerobic fermentation system. The extracellular product yield is increased through the use of an organism modified to decreased production of polyhydroxyalkanoate, to increase production of the extracellular product, and to include promoters that can be inducible in response to nutrient limitation conditions. The extracellular product yield is also increased by operating the continuous fermentation system under particular nutrient limitation conditions. Also provided are non-naturally occurring organisms that have been modified for use with the provided methods, and extracellular products made using the provided methods.