The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2024
Filed:
Apr. 19, 2019
Merck Sharp & Dohme Llc, Rahway, NJ (US);
Adam Kristopeit, Lansdale, PA (US);
Janelle Konietzko, Lansdale, PA (US);
Wanli Ma, Lansdale, PA (US);
Katherine Phillips, Audubon, PA (US);
Andrew Swartz, Chalfont, PA (US);
Sheng-Ching Wang, Eagleville, PA (US);
Marc D. Wenger, Allentown, PA (US);
Matthew Woodling, Lansdale, PA (US);
Tiago Matos, Philadelphia, PA (US);
Merck Sharp & Dohme LLC, Rahway, NJ (US);
Abstract
The present invention relates to a scalable process for the purification of human cytomegalovirus particles from cell culture medium. In particular, the process involves a two step chromatography process starting with an anion exchange chromatography step followed by a polishing chromatography step selected from mixed mode chromatography or cation exchange chromatography.