The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2024
Filed:
Aug. 01, 2018
Applicant:
Cevec Pharmaceuticals Gmbh, Cologne, DE;
Inventors:
Assignee:
CEVEC Pharmaceuticals GmbH, Cologne, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); C07K 14/71 (2006.01); C07K 19/00 (2006.01); C12N 5/07 (2010.01); C12N 5/071 (2010.01); C12N 5/10 (2006.01); C12N 5/16 (2006.01); C12N 15/09 (2006.01); C12N 15/113 (2010.01); C12N 15/62 (2006.01); C12N 15/63 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C12N 15/62 (2013.01); C07K 14/70517 (2013.01); C07K 14/71 (2013.01); C07K 19/00 (2013.01); C12N 5/06 (2013.01); C12N 5/0625 (2013.01); C12N 5/10 (2013.01); C12N 5/16 (2013.01); C12N 15/09 (2013.01); C12N 15/1138 (2013.01); C12N 15/63 (2013.01); C12N 15/85 (2013.01); C07K 2319/00 (2013.01); C12N 2501/105 (2013.01);
Abstract
The present invention relates to methods for the selection of a stable producer cell line expressing one or more protein(s) of interest (POIs), comprising the stable transfection of cells with a gene encoding a constitutively active variant of a growth factor receptor, respective methods for the expression of one or more POIs in such stable producer cell lines, and uses of a constitutively active variant of a growth factor receptor as selection marker in the cultivation of cells.