The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2024
Filed:
May. 13, 2022
Yale University, New Haven, CT (US);
University of Connecticut, Farmington, CT (US);
Farida Ahangari, New Haven, CT (US);
Naftali Kaminski, New Haven, CT (US);
Carlos Fernandez-Hernando, New Haven, CT (US);
Raman Bahal, Glastonbury, CT (US);
YALE UNIVERSITY, New Haven, CT (US);
UNIVERSITY OF CONNECTICUT, Farmington, CT (US);
Abstract
In one aspect, the present disclosure provides a microRNA-33 (miR-33) inhibitor comprising a peptide nucleic acid covalently bound to a pH low insertion peptide. In another aspect, the present disclosure provides a method of treating pulmonary fibrosis in a subject, the method comprising administering to the subject a therapeutically effective amount of the miR-33 inhibitor. In some embodiments, the pulmonary fibrosis is idiopathic pulmonary fibrosis.