The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2024
Filed:
Jun. 27, 2019
Applicant:
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Inventors:
Nathanael Gray, Boston, MA (US);
Tinghu Zhang, Brookline, MA (US);
Eric Fischer, Chestnut Hill, MA (US);
Alyssa Verano, Allston, MA (US);
Zhixiang He, Brookline, MA (US);
Guangyan Du, Jamaica Plain, MA (US);
Katherine Donovan, Boston, MA (US);
Radoslaw Nowak, Boston, MA (US);
Jing Ting Christine Yuan, Brookline, MA (US);
Assignee:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/14 (2006.01); A61K 31/5517 (2006.01); A61K 47/54 (2017.01); A61K 47/55 (2017.01); A61P 35/00 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 495/14 (2013.01); A61K 47/545 (2017.08); A61K 47/55 (2017.08); A61P 35/00 (2018.01);
Abstract
Disclosed are degraders, pharmaceutical compositions containing them, and methods of making and using the degraders to treat diseases and disorders characterized by aberrant protein activity that can be targeted by cereblon.